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KMID : 0376419940180010065
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Chonbuk University Medical Journal
1994 Volume.18 No. 1 p.65 ~ p.72
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Clinical Study of 21 Cases of Adult Polycystic Kidney Disease
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송항용
김정은/강원택/김원/박성광/강성귀
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Abstract
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Background:
@EN Adult polycystic kidney disease(ADPKD) is a hereditary disorder transmitted by autosomal dominant gene(s), and characterized by multiple cysts on kidneys and many other organs. There are about half million patients with ADPKD in United
States.
In
Korea, approximately 1-2% of the patients on dialysis have ADPKD.
@ES Methods:
@EN To develop the profile of the ADPKD, we analysed clinical characteristics of 21 patients retrospectively.
@ES Results:
@EN In this series, 57% of the patients were in the 6th to 7th decades of life at the time of diagnosis. And male and female ratio was 1 : 1.6. On admission, symptom and sign were headache(47.6%) and flank pain(28.6%), palpable kidney(48%) and
hypertension(33%). Cyst in the liver(48%) was major extrarenal lesion, and there was one case of cyst in spleen. Thrity percent of patients revealed normal urine findings on admission. Eight patients were diagnosed as having chronic renal failure
on
admission. Three cases of them were treated with dialysis, and one case of them hd renal transplantation. The incidence of positive family history was just only 13.4%.
@ES Conclusion:
@EN We suspect three are many families with adult polycystic kidney disease in Korea. Therefore, we should place emphasis on early detection and management of adult polycystic kidney disease.
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